PROFESSOR DR. TENGKU SIFZIZUL BIN TENGKU MUHAMMAD
Institute of Climate Adaptation & Marine Biotechnology
sifzizul@umt.edu.my
https://wise.umt.edu.my/sifzizul
Executive Summary
-
Expertise
LIFE SCIENCES
Biological Sciences
Genes and Genomes Biology
Gene Expression Analyses
Publications
Indexed Journal (Scopus & Wos)
Non-Indexed Journal
Books
Chapter In Books
Proceedings
RM3,306,842.90
Approved Grants
26
H-Index (Scopus)
16
Number of Projects
14
Total Postgraduate Students
PUBLICATIONS
Journals
Note: This list is compiled based on data from the last five years.
| No. | Article Title | Year | Journals | Indexing | Authorship |
|---|---|---|---|---|---|
| 1 | Antibacterial Activity Of Chito-oligosaccharides Derived From Fish Scales | 2022 | Research Journal Of Pharmacy And Technology | Scopus | Co Author |
| 2 | Comprehensive Review On Mechanistic Insights, Optimal Dosages, And Safety Prospective Of Natural Products In Anticancer Therapeutics | 2024 | Food And Drug Safety | Google Scholar | Co Author |
| 3 | Cytotoxic Effect And Apoptotic Induction Of Tricyclohexyltin P-methoxycinnamate On Ht-29 Colorectal Cancer Cells: Implications For Anticancer Therapeutics | 2025 | Journal Of Advanced Pharmaceutical Technology And Research | Scopus | Co Author |
| 4 | Cytotoxicity Assays For Cancer Drug Screening: Methodological Insights And Considerations For Reliable Assessment In Drug Discovery: [ensaios De Citotoxicidade Para Triagem De Drogas Contra O Câncer: Insights Metodológicos E Considerações Para Avaliação Confiável Na Descoberta De Drogas] | 2024 | Brazilian Journal Of Biology | Scopus | Co Author |
| 5 | Effect Of Gracilaria Changii Extract And Its Fraction In Reverse Cholesterol Transport By Targeting Sr-bi Gene | 2024 | Natural Product Research | WoS | Co Author |
| 6 | Carbon Stock Estimation Of Selected Subtropical Broad-leaved Evergreen Scrub Forest | 2022 | Sustainability | WoS | Co Author |
| 7 | Anticancer Potential Of Three Sea Cucumber Species Extracts On Human Breast Cancer Cell Line | 2022 | Squalen Bulletin Of Marine And Fisheries Postharvest And Biotechnology | Scopus | Co Author |
| 8 | Cancer And Apoptosis | 2022 | Methods In Molecular Biology (clifton, N.j.) | Scopus | Co Author |
| 9 | Dicyanoanilines As Potential And Dual Inhibitors Of Alpha-amylase And Alpha-glucosidase Enzymes: Synthesis, Characterization, In Vitro, In Silico, And Kinetics Studies | 2022 | Arabian Journal Of Chemistry | WoS | Co Author |
| 10 | Investigation Of Dual Effect Of Citric Acid On Preparation And Preservation Of Guava Jelly Via Physicochemical Analysis | 2024 | Research Journal Of Pharmacy And Technology | Scopus | Co Author |
| 11 | Chito-oligosaccharides Derived From Tilapia Fish Scales: A Powerful Antioxidant | 2023 | Research Journal Of Pharmacy And Technology | Scopus | Co Author |
| 12 | Formulation And Characterization Of Snedds Of Pandanus Tectorius Fruit Extract And In Vitro Antioxidant Activity | 2022 | Oriental Journal Of Chemistry | WoS | Co Author |
| 13 | Aaptamine Attenuates The Action Of Statin On Pcsk9 And Ldlr Expression As Well As Ldl-c Uptake In Human Liver Cells | 2026 | Journal Of Applied Pharmaceutical Science | Scopus | Co Author |
| 14 | Selected Coastal Plants As Potential Treatment For Pneumonia Disease: Determination Of Their Phytochemicals And Antibacterial Activity Against Some Pneumonia Bacteria | 2023 | Oriental Journal Of Chemistry | Non-Index | Co Author |
| 15 | Cancer And Disease Diagnosis-biosensor As Potential Diagnostic Tool For Biomarker Detection | 2022 | Journal Of Advanced Pharmaceutical Technology & Research | WoS | Co Author |
| 16 | Hsp70 Knockdown In The Brine Shrimp Artemia Franciscana: Implication On Reproduction, Immune Response And Embryonic Cuticular Structure | 2024 | Marine Biotechnology | WoS | Co Author |
| 17 | Effect Of Pectin And Citric Acid On Total Bacterial Load, Fungal Load, And Techno-economic Feasibility From Processing To The Storage Of Guava Jelly | 2023 | Research Journal Of Pharmacy And Technology | Scopus | Co Author |
| 18 | Antibacterial Activity Of Tilapia Fish Scales Derived Chitosan: Future Towards Biomedicines | 2023 | Research Journal Of Pharmacy And Technology | Scopus | Co Author |
| 19 | Combined Multivariate Statistical Techniques And Water Quality Index (wqi) To Evaluate Spatial Variation In Water Quality | 2023 | Tropical Life Sciences Research | Scopus | Co Author |
| 20 | Advancing Research On Proprotein Convertase Subtilisin/kexin Type 9 Inhibitors: A Scientometric Analysis | 2024 | Malaysian Journal Of Medical Sciences | Scopus | Corresponding Author |
| 21 | Methyl Benzoate From Acanthaster Planci Exhibits Lipid-lowering Activity In Hypercholesterolemic Sprague-dawley Rat???s Hepatocyte By Increasing Scavenger Receptor Class B Type 1 (sr-b1) Gene Expression | 2023 | International Journal Of Pharmaceutical Sciences And Research | Non-Index | Co Author |
| 22 | Effect Of Pectin And Citric Acid On Sensory Evaluation For Consumer’s Acceptability Of Preserved Guava Jelly | 2024 | Research Journal Of Pharmacy And Technology | Scopus | Co Author |
| 23 | Cancer And Apoptosis: The Apoptotic Activity Of Plant And Marine Natural Products And Their Potential As Targeted Cancer Therapeutics | 2022 | Frontiers In Pharmacology | Scopus | Co Author |
| 24 | Iron Deficiency Amongst University Graduates: Prevalence, Diagnosis, And Iron Consumption | 2023 | Archives Of Pharmacy Practice | WoS | Co Author |
| 25 | Melaleuca Cajuputi: Metabolites Profiling And Its Potential Against Biofouling | 2024 | Egyptian Journal Of Aquatic Research | Scopus | Co Author |
| 26 | Selected Coastal Plants As Potential Treatment For Pneumonia Disease: Determination Of Their Phytochemicals And Antibacterial Activity Against Some Pneumonia Bacteria | 2023 | Oriental Journal Of Chemistry | WoS | Co Author |
| 27 | Peatland Fires In Peninsular Malaysia Act As Primary Source Of Dioxins, Dioxin-like Polychlorinated Biphenyl, And Particulate Matter | 2025 | Environmental Monitoring And Assessment | WoS | Co Author |
| 28 | Cytotoxicity And 1h Nmr Metabolomics Analyses Of Microalgal Extracts For Synergistic Application With Tamoxifen On Breast Cancer Cells With Reduced Toxicity Against Vero Cells | 2022 | Heliyon | Scopus | Co Author |
| 29 | Acanthaster Planci Inhibits Pcsk9 Gene Expression Via Peroxisome Proliferator Response Element (ppre) And Activation Of Mek And Pkc Signaling Pathways In Human Liver Cells | 2022 | Pharmaceuticals | Scopus | Corresponding Author |
| 30 | Exposure To Pcdd/fs From Peatland Fires Induces Oxidative Stress Among Fire-fighters In Peninsular Malaysia | 2023 | Malaysian Journal Of Medicine And Health Sciences | Scopus | Corresponding Author |
| 31 | Effect Of Linoleic Acid On Cholesterol Levels In A High-fat Diet-induced Hypercholesterolemia Rat Model | 2023 | Metabolites | Scopus | Co Author |
| 32 | The Interplay Of Inflammation And Gut-microbiota Dysbiosis In Alzheimer`s Disease: Mechanisms And Therapeutic Potential | 2025 | International Journal Of Molecular Sciences | WoS | Co Author |
| 33 | The Interplay Of Inflammation And Gut-microbiota Dysbiosis In Alzheimer’s Disease: Mechanisms And Therapeutic Potential | 2025 | International Journal Of Molecular Sciences | Scopus | Co Author |
| 34 | Proximate And Mineral Analysis Of The Mushroom Biscuits | 2025 | Food Research | Scopus | Co Author |
| 35 | Effects Of Heat Shock Protein 70 Knockdown On The Tolerance Of The Brine Shrimp Artemia Franciscana To Aquaculture-related Stressors: Implications For Aquatic Animal Health And Production | 2022 | Aquaculture | Scopus | Co Author |
| 36 | Diisooctyl Phthalate Isolated From Rourea Mimosoides: A Partial Ppar¿ Agonist Potently Blocks Adipocyte Differentiation | 2022 | Tropical Journal Of Natural Product Research | Scopus | Co Author |
| 37 | Snedds To Improve The Bioactivities Of Pandanus Tectorius Leaves: Optimization, Antioxidant, And Anticancer Activities Via Apoptosis Induction In Human Cervical Cancer Cell Line | 2024 | Journal Of Applied Pharmaceutical Science | Scopus | Co Author |
| 38 | Antibacterial Activity Of Hexane And Methanol Fractions Of Some Selected Plants Against Klebsiella Pneumoniae | 2023 | Journal Of Advanced Pharmaceutical Technology And Research | Scopus | Co Author |
| 39 | Xestospongia Muta Fraction-7 And Linoleic Acid: Effects On Sr-bi Gene Expression And Hdl Cholesterol Uptake | 2023 | Marine Drugs | WoS | Co Author |
| 40 | Cutaneous Transcriptomic Profiling And Candidate Pigment Genes In The Wild Discus (symphysodon Spp.) | 2023 | New Zealand Journal Of Zoology | Scopus | Co Author |
| 41 | Polymeric Nanoparticles Methods Of Preparation And Drug Release Models: Effectiveness Towards Drug Delivery Systems | 2022 | Research Journal Of Pharmacy And Technology | Scopus | Co Author |
| 42 | Comparative Transcriptome Analysis Reveals Differential Cutaneous Gene Expression In The Color Variation Of Two Ornamental Discus, Red Melon And Red Cover | 2024 | Pigment Cell & Melanoma Research | WoS | Co Author |
Books
| No. | Book Title | Year | Publisher | Authorship |
|---|---|---|---|---|
| 1 | Modern Trends And Challenges In Research Of Marine Biodiversity Resources | 2023 | Penerbit Umt |
Chapter In Books
| No. | Book Title | Chapter Title | Year | Publisher | Authorship |
|---|---|---|---|---|---|
| 1 | Interdisciplinary Cancer Research | Green And Blue Solutions: Natural Compounds From Plants And Marine Organisms Therapeutic Role In Induction Of Cancer Cell Death | 2024 | SPRINGER | Co Author |
| 2 | Modern Trends And Challenges In Research Of Marine Biodiversity Resources | Conclusions: Conservation And Management Of Marine Biodiversity Resources Through Innovative Research | 2023 | PENERBIT UMT | Co Author |
| 3 | Modern Trends And Challenges In Research Of Marine Biotechnology Resources | Introduction: Exploring Marine Biodiversity And Its Utilisation For Human Well-being | 2023 | PENERBIT UMT | Co Author |
Proceeding
| No. | Article Title | Year | Proceeding | Indexing | Authorship |
|---|
RESEARCH GRANTS
Note: This list is compiled based on data from the last five years.
| No. | Grant Title | Role | Level | Funder | Value (RM) | Status |
|---|---|---|---|---|---|---|
| 1 | Characterization And Determination Of Natural Products Derived From Coastal Plants That Enhance Adaptation Of Marine Fish Against Climate And Environmental Stressors | Project Leader | National | KPT | RM742,500.00 | In Progress |
| 2 | Antioxidant And Anti-hypercholesterolemia Activity Of Isolated Compounds From Selected Coastal Plants And Their Potential Application As Body Care And Pharmaceutical Products | Co-Researcher | International | BENGKULU UNIVERSITY, INDONESIA | RM90,000.00 | In Progress |
| 3 | Mechanism Of Chemo-sensitized Palladium Complexes On Ha-cd44 In Causing Apoptosis | Co-Researcher | National | KEMENTERIAN PENDIDIKAN TINGGI (KPT) | RM130,800.00 | In Progress |
| 4 | Elucidation Of The Molecular Mechanisms Of Aaptamine In Regulating The Reverse Cholesterol Transport: Towards Reducing The Progression Of Atherosclerosis | Project Leader | National | KEMENTERIAN PENDIDIKAN TINGGI (KPT) | RM146,500.00 | In Progress |
| 5 | Interference Of Heat Shock Protein 70 (hsp70) Synthesis In Penaeid Shrimp; Roles And Implications In Physiological Development, Vibrio Tolerance And Immune Response | Co-Researcher | National | KEMENTERIAN PENGAJIAN TINGGI (KPT) | RM154,800.00 | In Progress |
| 6 | Climate-adaptive, Inclusive, Nature-based Aquaculture (caina) In Malaysia And Solomon Islands | Co-Researcher | International | WORLDFISH FILIPINA | RM586,002.90 | In Progress |
| 7 | Unravelling The Metabolic Regulation Of Alzheimer`s Gut Microbiota And Its Effect On Immune Regulation And Morphology Of Gastrointestinal Tract In Mice | Co-Researcher | National | KEMENTERIAN PENDIDIKAN TINGGI (KPT) | RM184,970.00 | In Progress |
| 8 | Unravelling The Metabolic Regulation Of Alzheimer's Gut Microbiota And Its Effect On Immune Regulation And Morphology Of Gastrointestinal Tract In Mice | Co-Researcher | National | Kementerian Pengajian Tinggi (KPT) | RM184,970.00 | In Progress |
| 9 | Upscale Of Spf Brine Shrimp Artemia Biomass And Cysts Production For Application In Aquaculture | Co-Researcher | National | KEMENTERIAN PENGAJIAN TINGGI (KPT) | RM250,000.00 | In Progress |
| 10 | Elucidation Of The Molecular Mechanisms Of Aaptamine In Attenuating The Effects Of Statin On Pcsk9 Gene Expression And The Uptake Of Cholesterol By Liver Cells | Project Leader | National | Kementerian Pendidikan Malaysia (KPM) | RM165,500.00 | Completed |
| 11 | Determination Of The Gene Regulation Of Acute Phase Response Genes: Application Of Real-time Cpr | Project Leader | Private | CANVIO SDN. BHD. | RM60,000.00 | In Progress |
| 12 | Coastal And Tropical Plants As Potential Prevention Of Secondary Pneumonia Infection Due To Covid-19 Via Angiotensin-converting Enzyme 2 (ace2) Inhibition Pathway | Co-Researcher | International | UMT | RM110,000.00 | In Progress |
| 13 | Multi-targeted Mechnanistic Study Of Palladium Complexes And Glutathione Inhibitors Co-loaded Ha Nanoparticles On Cancer Cells | Co-Researcher | University | UMT | RM20,000.00 | In Progress |
| 14 | Elucidation Of Newly Developed Self-nano Emulsifying Drug Delivery Susyem (snedds)-lipid Pandanus Tectorius And Compounds For Atherosclerosis Via The Inhibition Of Hmgcr Enzyme Activity | Co-Researcher | National | Kementerian Pendidikan Malaysia (KPM) | RM172,000.00 | Completed |
| 15 | Rna Interference Of Heat Shock Protein 70 (hsp70) And Its Role On The Immune Status Of The Brine Shrimp Artemia Franciscana | Co-Researcher | National | Kementerian Pendidikan Malaysia (KPM) | RM124,000.00 | Completed |
| 16 | The Molecular Mechanisms Of Ketone Bodies-induced Autophagy In Human Adipocytes | Co-Researcher | National | KEMENTERIAN PENDIDIKAN TINGGI MALAYSIA | RM184,800.00 | In Progress |
TEACHING
Note: This list is compiled based on data from the last five years.
| No. | Subject Name | Degree Level |
|---|---|---|
| 1 | Cell And Molecular Biology | Bachelor |
| 2 | Cellular Biology And Biochemistry | Bachelor |
| 3 | Principles Of Genetics | Bachelor |
| 4 | Animal Biotechnology | Bachelor |
| 5 | Cell And Tissue Culture | Bachelor |
POSTGRADUATE STUDENT
Note: This list is compiled based on data from the last five years.
| No. | Student Name | Degree | Status |
|---|---|---|---|
| 1 | Nurul Adila Binti Azemi | Doctor of Philosophy | Completed |
| 2 | Nurjannatul Naim Binti Kamaruddin | Doctor of Philosophy | Completed |
| 3 | Allicia Anak Jack | Doctor of Philosophy | Completed |
| 4 | Lukman Hakim Bin Mohd Din | Doctor of Philosophy | Ongoing |
| 5 | Ahmad Shalihin Bin Mohd Samin | Doctor of Philosophy | Completed |
| 6 | Thirukanthan Chandra Segaran | Doctor of Philosophy | Completed |
| 7 | Abdul Matin | Doctor of Philosophy | Completed |
| 8 | Zeenia | Doctor of Philosophy | Ongoing |
| 9 | Ina Monica Firsty | Doctor of Philosophy | Ongoing |
| 10 | Ayesha Ameen | Doctor of Philosophy | Ongoing |
| 11 | Liyana Binti Khairul Annuar | Master | Ongoing |
| 12 | Alifa Husnun Kholieqoh | Master | Completed |
| 13 | Nur Emylia Farhana Binti Abdul Khalil | Master | Ongoing |
| 14 | Murni Nur Islamiah Binti Kassim | Master | Ongoing |
INTELLECTUAL PROPERTIES
Note: This list is compiled based on data from the last five years.
| No. | IP Title | IP Type | IP Status | Reference ID | Year |
|---|
CONSULTANCY
Note: This list is compiled based on data from the last five years.
| No. | Title | Date | Level | Client Name |
|---|
KNOWLEDGE TRANSFER
Note: This list is compiled based on data from the last five years.
| No. | Title | Year | Level | Collaborator | Funder |
|---|
AWARDS
| No. | Name of Awards/Recognition | Awarding Institution | Year Awarded | Level |
|---|---|---|---|---|
| 1 | Darjah Setia Mahkota Terengganu (s.m.t.) | Kebawah Duli Yang Maha Mulia Sultan Terengganu | 2023 | National |
